Thanks everyone for the well wishes. After spending 4 long days and over 2900 miles, I've finally made it and for the most part intact. Here are my experiences:
First of all I am driving the EX 6MT trim. I would say that I was on ECON mode about 95% of the time and other 5% on Normal. My average speed was 55 Mph and on highway at about 62 Mph. My average fuel economy was 43 MPG.
My overall experience was pretty good though after about 6 hours of continuos driving, my right butt cheek and my back was sore and uncomfortable. And since the ceiling is pretty low and me being 5'8", sometimes it was a chore stretching my neck or even finishing a water bottle. You have to almost slouch just to get the last bit of water out. I highly recommend Cruise Control. By the way I was averaging about 13 hours of driving per day.
My CRZ's performance experience was positive for the most part. I tried not to speed even if the speed limit was 75mph. I was purposefully delicate with the ride. The only thing that really sucked was driving up major elevation which you will encounter around Kentucky, New Mexico, Arizona, and California. I tried to stay in ECON mode for those but you really feel the sluggishness of that mode. In fact at one point I was decelerating rapidly on 6th gear - had to downshift to 4th or even 3rd to have enough torque to get up. Pretty scary and you will use up the battery assist in matter of seconds. Luckily the car has Normal mode for added power or even Sports Mode.
One of the great things about this car is the amount of head turning that you will get while on the road. I tried to be extra careful to avoid as much road pebbles kicking up at the car and scratching. I did notice that there was a slight paint chip next to the right fog light. I guess I'll have to purchase a touch up paint to cover that. I'm going to wash and thoroughly check to car tomorrow to make sure there are no other scratches or chips.
But on another note not related to the actual travel, I think someone backed into my car while parked because there is a slight indentation on the front bumper on the right at the seam of the front hood. I just noticed it when I parked at night next to a street light and that area was darker due to the shadow. I ran my finger over the entire seam from left to right and I can definitely feel it. Though there doesn't appear to be a scratch or a paint chip. Strange. Will have to check it out in the morning.